With its diverse landscape and established cross-state routes, Missouri has a strong reputation for long-distance cycle touring. The Show Me State is already home to two U.S. Bicycle Routes — USBR 66 and 76, which cut through its heart from east to west — as well as the iconic Katy Trail, the longest continuous recreational rail-trail in the country. (Catch the full Katy Trail thru-ride experience here.)

But now, there’s a new way to explore Missouri on two wheels, and it’s no easy ride. Enter USBR 51, the first official cycling route to slice north-south through the state. The route begins at the Missouri-Iowa border on U.S. Highway 69 and winds its way down to the Missouri-Arkansas border at U.S. Highway 71, connecting with Arkansas’ own USBR 51 for an impressive total length of 553.7 miles.

Introduced in fall 2024 alongside routes USBR 37 in Indiana and USBR 50 and 55 in Kansas, USBR 51 travels a mix of scenic state and local roadways, coupled with off-road gems like the Katy Trail near Sedalia, the serene paths of Watkins Woolen Mill State Park in Lawson, the iconic Swinging Bridge Trail near Warsaw (pictured), and the historic Frisco Highline Trail that cuts through the Ozarks from Bolivar to Springfield.

The U.S. Bicycle Route System is a growing network that aims to connect communities across the country, offering a seamless, numbered, and signed system of roads and trails designed for cyclists. With over 23,000 miles of routes already in place, this system isn’t just about recreation — it’s a lifeline for communities, expanding transportation options, boosting tourism, and fueling local economies.

USBR 51 is the first official cycling route to slice north-south through Missouri. (Adventure Cycling Association)

The Adventure Cycling Association (ACA) and American Association of State Highway and Transportation Officials (AASHTO), which facilitate the U.S. Bicycle Route System, worked with the Missouri Bicycle and Pedestrian Federation and public advocates to ensure the roads and trails chosen for USBR 51 provide a truly bike-friendly experience.

“We’re committed to delivering a safe, multimodal transportation system that enhances mobility for everyone,” says Jim Tymon, executive director of AASHTO. “Our partnership with the Adventure Cycling Association to expand the U.S. Bicycle Route System reflects our dedication to creating better travel options for all.”

Ready to ride? Digital maps for all U.S. Bicycle Routes, including the newly designated USBR 51, are available for free on the ACA website here.

Author: Brad Kovach is the publisher of Terrain.

Top image: Cyclists ride across the Swinging Bridge, part of the new USBR 51 bicycle route. (Adventure Cycling Association)